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Service 42  City Centre - Mutley Plain - Crownhill - Derriford Hospital - Marjons - George Park & Ride - Mainstone
 
From Royal Parade via St Andrews Cross Roundabout, Exeter Street Viaduct, Charles Cross Roundabout, Charles Street, Drake Circus [Plymouth University/The Box], North Hill, Mutley Plain, Mannamead Road, Manadon Roundabout, Tavistock Road [Crownhill Low Level], Derriford Roundabout, [Derriford Hospital], Marjons Link Road, Runway Road, Tavistock Road, [George Park and Ride], Morgan Road, Plymbridge Road, B3432, [Estover Industrial Estate], Novorossiysk Road, Colwill Road, Weir Road, [Mainstone], Pattinson Drive, Miller Way to [Asda Estover]
 
Service 42  Mainstone - George Park & Ride - Marjons - Derriford Hospital - Crownhill - Mutley Plain - City Centre
 
From Asda Estover via Miller Way, Pattinson Drive, [Mainstone], Weir Road, Colwill Road, Novorossiysk Road, [Estover Industrial Estate], B3432, Plymbridge Road, Morgan Road, [George Park & Ride], Tavistock Road, Runway Road, Marjons Link Road, [Derriford Hospital], Derriford Roundabout, Tavistock Road [Crownhill Low Level], Manadon Roundabout, Mannamead Road,  Mutley Plain, North Hill, Drake Circus [The Box/Plymouth University], Cobourg Street, Mayflower Street, Western Approach, Union Street and Derrys Cross Roundabout to Royal Parade
 
Service 42C  City Centre - Mutley Plain - Crownhill - Derriford Hospital - Marjons - George Park & Ride - Woolwell
 
From Royal Parade via St Andrews Cross Roundabout, Exeter Street Viaduct, Charles Cross Roundabout, Charles Street, Drake Circus [Plymouth University/The Box], North Hill, Mutley Plain, Mannamead Road, Manadon Roundabout, Tavistock Road [Crownhill Low Level], Derriford Roundabout, Derriford Road, Derriford Hospital, Marjons Link Road, Plymbridge Lane, Runway Road, Tavistock Road [George Park & Ride], Woolwell Roundabout and Woolwell Road [Tesco] to Woolwell Road [School Drive], Pick Pie Drive to Woolwell [Church Park Road].  
 
Service 42C  Woolwell - George Park & Ride - Marjons - Derriford Hospital - Crownhill - Mutley Plain - City Centre
 
From Woolwell [Church Park Road] to Pick Pie Drive, Woolwell Road [School Drive] via Woolwell Road [Tesco], Woolwell Roundabout, Tavistock Road [George Park & Ride], Runway Road, Plymbridge Lane, Marjons Link Road, Derriford Hospital, Derriford Road, Derriford Roundabout, Tavistock Road [Crownhill Low Level], Manadon Roundabout, Mannamead Road,  Mutley Plain, North Hill, Drake Circus [The Box/Plymouth University], Cobourg Street, Mayflower Street, Western Approach, Union Street and Derrys Cross Roundabout to Royal Parade